Publications 

 

Dragoi D, Benesic A, Pichler G, Kulak NA, Bartsch HS and Gerbes AL

Proteomics Analysis of Monocyte-Derived Hepatocyte-Like Cells Identifies Integrin Beta 3 as a Specific Biomarker for Drug-Induced Liver Injury by Diclofenac.

Front Pharmacol. 2018; 9: 699.Published online 2018 Jul 4. doi:  10.3389/fphar.2018.00699


EMJ Hepatology 6.1. 2018


 

Benesic A and Gerbes AL

Herbal tea and liver injury - Tea extract or comedication can make a difference. Journal of Hepatology. Published online May 15 2018. DOI:10.1016/j.jhep.2018.03.033

 


Benesic A, Rotter I, Dragoi D, Weber S, Buchholtz ML, Gerbes AL

Development and Validation of a Test to Identify Drugs That Cause Idiosyncratic Drug-induced Liver Injury. Clinical Gastroenterology and Hepatology (2018). Published online April 30, 2018. DOI: 10.1016/j.cgh.2018.04.049
 


Kullack-Ublick GA, Andrade RJ, Merz M, End P, Benesic A, Gerbes AL and Aithal GPDrug-induced liver injury: recent advances in diagnosis and risk assessment. Gut (2017) Jun 66(6) 1154-64https://www.ncbi.nlm.nih.gov/pubmed/28341748 


 Benesic A and Gerbes ALDrug-induced Liver Injury and individual cell models. Digestive Diseases (2015); 33(4) 2015http://www.karger.com/Article/Pdf/374094


 Benesic A, Leitl, A and Gerbes AL

Monocyte-derived hepatocyte-like cells for causality assessment of idiosyncratic drug-induced liver injury. Gut (2015) online first June 4 2015; Gut doi-10.1136: gutjnl-2015-309528

http://gut.bmj.com/content/early/2015/06/04/gutjnl-2015-309528.abstract


 

Benesic A, Rahm NL, Ernst S and Gerbes AL

Human monocyte-derived cells with individual hepatocyte characteristics: a novel tool for personalized in vitro studies. Laboratory Investigation (2012) 92, 926–936; doi:10.1038/labinvest.2012.64; published online 2 April 2012

http://www.nature.com/labinvest/journal/v92/n6/abs/labinvest201264a.html

 

 

 

 

Proceedings

 

Benesic A, Dragoi D, Pichler G, Kulak N, Bartsch H, Gerbes AL

MH cells in combination with proteomics identify a potential biomarker for Drug-induced Liver Injury by Diclofenac. J Hepatol 2018; 68(1) S589


 

Webinar: Research Highlights from the FDA Drug-Induced Liver Injury Conference 2015-2016


 

Combining MetaHeps® and Proteomics to identify Biomarkers of idiosyncratic drug-induced liver injury. Andreas Benesic, Diana Dragoi, Garwin Pichler, Nils Kulal and Alexander L Gerbes. AASLD Liver Meeting® 2016. Boston, USA

 
A NOVEL IN VITRO TEST ALLOWS CAUSALITY ASSESSMENT OF DRUG INDUCED LIVER INJURY IN POLYMEDICATION. Andreas Benesic, Sandra Ehrlich and Alexander Gerbes. International Liver Congress 2016. Barcelona, Spain

 

Tranforming monocytes into Hepatocyte surrogates. Andreas Benesic and Alexander L Gerbes. XV. FDA/CDER/PhRMA DILI Conference, Maryland USA; 03/2015


 

Prevention of Drug-Induced Liver Injury by a Personalized Novel Cell Model. Andreas Benesic, Romina M. Wiedmann and Alexander L. Gerbes. 3rd Munich Biomarker Conference; 11/2013


 

Human Autologous Blood Cells as an Enabling Tool for Prediction of Individual Drug Toxicity – Metaheps for Metabolic Phenotyping. Andreas Benesic, Alexander L. Gerbes; 1st Munich Biomarker Conference; 11/2011


 

Expression und Funktion von CYP P450 Isoenzymen in Metaheps – Hepatozytenähnliche Zellen monozytären Ursprungs. Andreas Benesic, Enrico de Toni Veit Gülberg, Alexander L. Gerbes; 116. Internistenkongress; 04/2010


 

Metaheps exhibit CYP P450 metabolism - induction by ethanol, phenytoin and dexamethasone. Z Gastroenterol 2009; 47 Andreas Benesic, Nora L. Rahm, Samuel Ernst, Enrico de Toni, Maria Escobar, Veit Gülberg, Alexander L. Gerbes; DGVS; 09/2009


 

In vitro labelling of transformed human peripheral Monocytes with supraparamagnetic iron oxides does not alter viability and biochemical characteristics.Andreas Benesic, Frank Berger, Samuel Ernst, Enrico de Toni, Veit Gülberg, Alexander L. Gerbes; 19. Workshop für experimentelle und klinische Hepatologie und Lebertransplantation 05/2009


 

In vitro transformed peripheral monocytes exhibit several hepatocyte-like characteristics: a functional analysis Andreas Benesic, Samuel Ernst, Enrico de Toni, Markus Bystron, Veit Gülberg, Christine Opelz, Alexander L. Gerbes; GASL; 02/2008


 

In vitro transformation of peripheral monocytes to progenitor cells with putative hepatopoetic potential and their labeling with supraparamagnatic iron oxides for MR-analysis. Andreas Benesic, Frank Berger, Markus Bystron, Enrico de Toni, Veit Gülberg, Alexander L. Gerbes; 16. Jahrestagung der Deutschen Transplantationsgesellschaft vom 11-14. Oktober in Mainz; 10/2007


 

In vitro transformation of peripheral monocytes to putative hepatopoetic progenitors with hepatocyte-like glucagon responsiveness Andreas Benesic, Enrico de Toni, Markus Bystron, Veit Gülberg, Christine Opelz, Alexander L. Gerbes; 62. Jahrestagung der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten 12.-15.September 2007 in Bochum; 09/2007 


 

In vitro transformation of peripheral monocytes to progenitor cells with putative hepatopoetic potential. Andreas Benesic, Enrico de Toni, Markus Bystron, Veit Gülberg, Alexander L. Gerbes; 18. Workshop für experimentelle und klinische Hepatologie und Lebertransplantation, 14- 16. Juni 2007 in Wilsede; 06/2007

 

 

 

Andreas Benesic on ResearchGate